Enhances water retention in nucleus
pulposus of spinal discs;
improves disc
height, flexibility, and shock absorption.
Provides the primary collagen structure in cartilage and intervertebral discs;
support
tensile strength and resilience.
Cofactor for proline and lysine hydroxylation in collagen formation;
essential for maintaining connective tissue integrity.
Works synergistically with glucosamine to
promote
cartilage hydration and inhibit
matrix-degrading enzymes.
Precursor for glycosaminoglycans (GAGs);
stimulates chondrocyte activity and
proteoglycan synthesis for disc repair.
Inhibits 5-lipoxygenase (5-LOX); reduces joint
inflammation and stiffness
in load-bearing joints.
Provides the primary collagen structure in cartilage and intervertebral discs;
support
tensile strength and resilience.
Lubricates joints, supports anti-inflammatory cytokine
balance (↓ TNF-α, ↑ IL-10); helps cushion joints during motion
Antioxidant; cofactor for collagen synthesis in joint tissue.
Neutralizes oxidative stress in joint tissues; supports recovery from mechanical stress.
Fundamental for hydroxyapatite crystal
formation in long bones;
citrate form
improves absorption.
Cofactor for over 300 enzymes; essential for bone remodeling,
PTH regulation,
and calcium uptake
Activates osteocalcin and matrix Gla-protein;
ensures calcium is directed to bone, not arteries.
Enhances intestinal absorption of calcium and phosphate; regulates bone turnover.
Promotes osteoblast activity, collagen synthesis, and growth plate development
Assists in calcium absorption and collagen synthesis; essential for bone tissue regeneration.
Promotes nitric oxide (NO) release;
stimulates pituitary GH secretion by
suppressing somatostatin.
Works synergistically with arginine; supports GH pulse amplitude and ammonia detoxification.
Required for GH synthesis and receptor function;
supports protein metabolism
and tissue repair.
Provides direct building blocks for connective tissue repair and elasticity.
Precursor for glycosaminoglycans (GAGs);
stimulates chondrocyte activity and
proteoglycan synthesis for disc repair.
Cofactor in amino acid metabolism and GH signaling; supports collagen cross-linking.
Cofactor for over 300 enzymes; essential for bone remodeling,
PTH regulation,
and calcium uptake
Enhances motor learning, attention, and neuromuscular firing;
may improve coordination of postural stabilizers.
Reduces cortisol, improves neuromuscular resilience under stress;
supports parasympathetic balance
Enhances alpha wave activity; promotes relaxed, upright posture and balanced muscle tone.
Supports nerve myelination and neuromuscular signaling;
essential for
proprioceptive feedback and posture
awareness.
Clinically shown to increase amino acid and
vitamin absorption by 40–60%
extract) in intestinal lining.
Enhances nutrient absorption via intestinal enzyme modulation;
improves
bioavailability of curcumin, amino acids.
Supports gut microbiome balance, improves digestive enzyme activity,
and
reduces nutrient malabsorption.
Breaks down proteins, fats, and carbs to improve absorption
of collagen peptides,
vitamins, and minerals.
Supports growth plate flexibility, chondrocyte activity,
and bone regeneration; modulates estrogenic and IGF-1 pathways.
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